Larkin -- who was enshrined in the Baseball Hall of Fame in July -- will be honored with "11 Days of Larkin," a series of celebrations beginning Aug. 16.
"My family and I are very excited about the special celebration in Cincinnati," Larkin said in a statement released by the Reds. "Since January, the entire Hall of Fame experience has been a dream for us, and the upcoming weekend will be a fitting end to an incredible summer."
It will be the 10th jersey retired by the Reds. The others are Fred Hutchinson, No. 1; Johnny Bench, No. 5; Joe Morgan, No. 8; Sparky Anderson, No. 10; Dave Concepcion, No. 13; Ted Kluszewski, No. 18; Frank Robinson, No. 20; Tony Perez, No. 24; and Jackie Robinson, No. 42.
"I am going to be very excited and humbled when my uniform number is retired next to those of players I grew up admiring and respecting," Larkin said. "I'm looking forward to celebrating this honor with my hometown fans. I want this to be a celebration about all Cincinnatians who have made the city proud."